Biopharma Processing
 
     
Biopharmaceuticals are pharmaceutical products that contain biotechnology derived proteins as active substances.

Over the years a very large number of different biomolecules and their importance / role in various biochemical processes have been researched upon which in turn has thrown up many different types of biopharmaceutical products for various applications in the field of therapeutics and medical diagnostics.

 

Biopharma Processing

These can be categorized into the following groups but are not limited to: The manufacturing processes for most of different biopharmaceuticals have four major generic operations as shown in table below.

mdi offers a very wide range of microfiltration devices for media preparation, sterile venting, clarification of cell harvest and bioburden reduction and sterilization of a variety of fluid streams in the upstream as well as downstream process areas.
 
 
 
  • Cell Culture & Fermentation
  • Harvesting and Clarification
  • Purification
  • Aseptic Fill & Finish

 Mammalian Cell Culture
   - Media Preparation 
   -  Sterile venting 

  Microbial Fermentation (Click...)
  -  Sterile venting
  -  Sterile air sparging
  -  Sterile Filtration of growth regulators
  -  Sterile filtration of alkaline/acidic solutions for pH control 

      

  Harvesting and Clarification
   -  Mammalian Cell Culture Clarification
   -  Microbial Fermentation Broth Clarification


 
     Down Stream Processing (Click...)
 
 
 
 

  Aseptic Fill and Finish (Click..)
   -  Sterilization of buffer
   -  Sterilization of product
   -  Sterilization of air/gases
   -  Sterile venting
 
 
 


 
 
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  Biopharmaceuticals
- Recombinant Proteins
- Vaccines
- Plasma Fractions
- Monoclonal Antibodies

 Bioprocessing
  Cell Culture and Fermentation
  - Mammalian Cell Culture
  - Microbial Fermentation
  Harvesting and Clarification
  - Mammalian Cell Culture Clarification
  - Microbial Fermentation
Broth Clarification
  Downstream Processing
  Aseptic Fill and Finish

 
 
 
 
 
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