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AseptiCap NS 5, 10, 20, 30

AseptiCap® NL/NS Large

MDI AseptiCap NL/NS Nylon 66 membrane capsule filters are sterilizing grade filters offering absolute retention, wide chemical compatibility, and very low hold up volumes.

  • Single Layered: AseptiCap NL
  • Multiple Layered:AseptiCap NS

  • Absolute retention
  • 100% integrity tested
  • Very low hold up volume in filters
  • High flow rates
  • Serial construction with prefilter for higher throughput with fouling streams
  • Bioburden maintained below 1000 cfu/device
  • Endotoxin level certified to be <0.25 EU/ml
  • Widest range of end connections
  • Products available for total scalability from a few ml to thousands of liters
  • Total traceability through unique serial number for each filter
  • Individual certificate of quality for each device
  • Sterilizable by EO gas or autoclaving

 

  • Sterilizing filtration of stability batches in formulation development tabs.
  • Sterilization of Compatible solvents and chemicals.

Construction
Membrane Nylon 66
Final Filter Pore Size
0.2µm 0.45µm
Prefilter Pore Size
0.8µm, 0.45µm 0.8µm
Support Layers Polyester
Body and Core Polypropylene
Size
Size
5″ 10″ 20″ 30″
Effective Filtration Area (Nominal)
3000cm² 6000cm² 12000cm² 18000cm²
Dimension (End to End) – ¾” Sanitary Flange I/O
212 mm 345 mm — —
Dimension (End to End) – 1½” Sanitary Flange I/O
207 mm 326 mm 605 mm 865 mm
Dimensions (End to End) Inline Capsule Filters – 1½” Sanitary Flange Inlet ½” Single Step Hose Barb Outlet
212 mm 332 mm 618 mm 878 mm
Dimensions (End to End) Inline Capsule Filters – ½” Single Step Hose Barb I/O
217 mm 332 mm 628 mm 888 mm
Dimension (End to End) – 1″ Hose Barb I/O
— 405 mm 635 mm 895 mm
Operational Radius (with Vent/ Drain)
80 mm 80 mm 80 mm 80 mm
Dimension (End to End) – 3/8″ Hose Barb I/O
211 mm 330 mm 618 mm 878 mm
Vent and Drain ¼” Hose Barb with Silicone “O” rings
Integrity Testing / Retention
Microbial Retention
LRV >7 for Brevundimonas diminuta (ATCC 19146) per cm² LRV >7 for Serratia marcescens (ATCC 14756) per cm²
Air Diffusion Flow per 10″ Capsule filter (with 50% IPA Wetted)
< 30ml/min @ 37 psi (2.60 Kg/cm²) <30ml/min @ 22 psi (1.54 Kg/cm²)
Operational
Max. Operating Temperature 80 °C @ < 2 Kg/cm² (30 psi)
Max. Differential Pressure 4 Kg/cm² (60 psi ) @ 30 °C
Sterilization By Gas Sterilizable by Ethylene Oxide
Sterilization By Autoclave Autoclavable at 125 °C for 30 minutes and it cannot be in-line steam sterilized.
Shelf Life 3 years after EO Sterilization
Assurance
Toxicity Passes Bioreactivity test, In Vivo, as per USP <88> for Class VI plastics
Bacterial Endotoxin Aqueous extracts exhibit < 0.25 EU/ml as established by Limulus Amebocyte Lysate (LAL) Test as per USP <85>
Bioburden Bioburden level is < 1000 cfu/filter device as per ISO 11737-1 : 2018
Non Fiber Releasing Passes test as per USP and comply with USFDA 21 CFR Part 210.3(b)(6) for fiber release
Indirect Food Additive All Polypropylene components meet the FDA Indirect Food Additive requirements cited in 21 CFR 177.1520
Extractables with WFI Passes NVR test as per USP <661>
Good Manufacturing Practice These products are manufactured in a facility which adheres to Good Manufacturing Practices.
Oxidizable Substances Within limits as specified in USP <1231>
Particle Shedding Passes USP test for particulates in injectables.
TOC/Conductivity at 25 °C Meets the WFI requirements of USP <643> for Total Organic Carbon and USP <645> for Water Conductivity after a 3 liter of WFI flush
Quality Management System ISO-9001 Certified
USFDA DMF No. 015554

Type
AseptiCap NS
(0.45μm Upstream)*		 LNSX
AseptiCap NS
(0.8μm Upstream)		 LNS5
Size
Code
5″ 53
10″ 54
20″ 55
30″ 56
Pore Size
Code
0.2µm 01
0.45µm 02
I/O Connection
Connection Code
1½” Sanitary Flange E
3/4” Sanitary Flange**** S
3/8” Hose Barb*** I
Single Step ½” Hose Barb Q
1” Hose Barb** Z
X
Inline/T-line
Code
Inline X
T-line** T
Sterility
Code
Non Sterile 1
EO Sterile 2
Pack Size
Code
1 01

*0.45μm Upstream is only available in 0.2μm Pore Size

**1” Hose Barb and T-line is not available in 5″ Capsule filter

**T-line Capsule Filters are available with 1½” Sanitary Flange I/O Connections only

***3/8″ Hose Barb is available only with Inline capsule filters

****3/4″ Sanitary Flange end connection is available only in 5″ and 10″ capsule filters

Example :

LNS5 54 01 EE X X 1 01

Example for Non Sterile: LNS55401EEXX101                  Example for EO Sterile: LNS55401EEXX201

File Type Download
Datasheet Download
COQ Download

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